Open AccessChanges of junctions of endothelial cells in coronary sclerosis: A review
Author(s) -
Zhang LiZi,
Lei Sun
Publication year - 2016
Publication title -
chronic diseases and translational medicine
Language(s) - English
Resource type - Journals
ISSN - 2589-0514
DOI - 10.1016/j.cdtm.2016.05.001
Subject(s) - medicine , coronary artery disease , cardiology , endothelial dysfunction , endothelial stem cell , endothelium , biochemistry , chemistry , in vitro
Atherosclerosis, the major cause of cardiovascular diseases, has been a leading contributor to morbidity and mortality in the United States and it has been on the rise globally. Endothelial cell–cell junctions are critical for vascular integrity and maintenance of vascular function. Endothelial cell junctions dysfunction is the onset step of future coronary events and coronary artery disease.