English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

It has been recognized that tissue engineering and regenerative medicine (TERM) offers the next generation technology for whole organ and tissue transplantation for diseased, failed or malfunctioned organs. Biomaterials might be the one of the important factors to apply the complete bio-organ using TERM techniques. Around 30 years ago, the primitive concept of “Gradient Surface” had been introduced to improve the biocompatibility for biomaterials. However, the gradient concept of surface property is changing now numerous kinds of physicochemical properties very recently. In this review, the importance of the concept of gradient, the historical evolution of experimental methodology for the manufacturing of gradient surface during last over ~30 years in my research group and finally perspective as enabling technologies for the TERM area are summarized

Evolution of gradient concept for the application of regenerative medicine