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Background Exercise can be used to unmask the functional impact of a residual narrowing and/or stiffening following treatment of aortic coarctation. Measurements of the hemodynamic response during exercise are, however, difficult to perform and not very accurate, as suspension of exercise during imaging can be required or a low temporal resolution might be insufficient at the high heart rates present during exercise. This work aims to predict central aortic hemodynamics during exercise using advanced modeling tools.

6.2 PREDICTING THE FUNCTIONAL IMPACT OF RESIDUAL AORTIC COARCTATION LESIONS DURING EXERCISE USING ADVANCED COMPUTER MODEL SIMULATIONS