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oil is considered safe, different skin reactions have been reported in association with its use, including irritative dermatitis, erythema, erythema multiforme-like eruption, linear IgA bullous disease, systemic hypersensitivity reactions, and anaphylaxis. In the cases described, we observed positive reactions to 5% tea tree oil and 20% colophony, considered as present relevance and cross reaction, respectively, in both patients. The cross reaction with colophony has been previously described in the literature. In the first case, we expanded the initial epicutaneous study to include ɑ-pinene and limonene, which were both negative. Limonene is one of the components of tea tree oil and a positive result for this substance may be key to suspecting a possible contact allergy to tea tree oil. Tea tree oil is an essential oil with considerable sensitizing power, especially in its oxidized form. Although allergic contact dermatitis due to this oil has been considered rare in our setting, the incidence has increased in recent years due to the popularity of alternative therapies and its presence in different commonly used products. In the epicutaneous tests, a positive result for limonene may be the key to suspecting possible contact allergy to tea tree oil and a cross reaction with colophony may be present. Since 1991, approximately 100 cases of allergic contact dermatitis due to tea tree oil have been reported, of which only 5 have been reported in Spain. We report 2 new cases, one of which is the first case of allergic contact dermatitis due to this essential oil in a girl in Spain.

Eritema papular semicircular recidivante: ¿nueva entidad o subtipo de eritema anular centrífugo?