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The one-dimensional hyperbolic Pennes bioheat equation under instantaneous moving heat source is solved analytically based on the Eigenvalue method. Comparison with results of in vivo experiments performed earlier by other authors shows the excellent prediction of the presented closed-form solution. We present three examples for calculating the Arrhenius equation to predict the tissue thermal damage analysis with our solution, i.e., characteristics of skin, liver, and kidney are modeled by using their thermophysical properties. Furthermore, the effects of moving velocity and perfusion rate on temperature profiles and thermal tissue damage are investigated. Results illustrate that the perfusion rate plays the cooling role in the heating source moving path. Also, increasing the moving velocity leads to a decrease in absorbed heat and temperature profiles. The closed-form analytical solution could be applied to verify the numerical heating model and optimize surgery planning parameters.

Analysis of hyperbolic Pennes bioheat equation in perfused homogeneous biological tissue subject to the instantaneous moving heat source