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HighlightsA polarized-macrophages-based drug delivery system (M1/SLNP) was presented for the cell-chemotherapy of cancer.    Polarized-macrophages were used both as therapeutic tool to provide immunotherapy and as delivery vessel to target deliver chemotherapeutic drugs to tumor tissues for chemotherapy simultaneously.    M1/SLNP was a multifunctional delivery system with simple structure, excellent safety, and without complex synthesis process.Electronic supplementary material  The online version of this article (10.1007/s40820-020-00531-0) contains supplementary material, which is available to authorized users.

Nanoparticle-Loaded Polarized-Macrophages for Enhanced Tumor Targeting and Cell-Chemotherapy