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A recent Canadian case-control study reported a 4.5-fold increased risk of retinal detachment (RD) during oral fluoroquinolone use. Of the fluoroquinolone-exposed cases, 83 % were exposed to ciprofloxacin. We sought to replicate this finding, and assess whether it applied to all fluoroquinolones.

Exposure to Oral Fluoroquinolones and the Risk of Retinal Detachment: Retrospective Analyses of Two Large Healthcare Databases