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Cardiac output monitors can be assessed by a variety of techniques, but a common principle is quantifying agreement between a reference standard and new monitor. The current standard analysis technique is a Bland-Altman plot. The Bland-Altman plot evaluates bias between mean differences of cardiac output, from which an agreement interval is derived. These limits are, however, statistical limits of agreement and the clinical acceptability will depend upon context and application. This article provides suggestions for understanding and presenting the results of cardiac output validation, using standard metrology alongside proposals for criteria used to accept new techniques.

Cardiac Output Monitoring: Validation Studies–how Results Should be Presented