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We thank Prof. Vock for his noteworthy and constructive commentary [1]. This gives us the opportunity to briefly provide additional observations to elaborate this topic further. We agree with Prof. Vock that our theoretical approach [2] may not be applied in a non-invasive and low-dose medical imaging. Nevertheless, this makes the innovation that we are trying to develop even more challenging. We are all discussing about something similar to a “paradigm shift”, in the sense described by Kuhn [3]: (a) presenting results “sufficiently unprecedented to attract an enduring group of adherents away from competing modes of scientific activity” and (b) “being sufficiently open-ended to leave all sorts of problems for the redefined group of practitioners to solve.”

insights into imaging

Response to invited commentary: “Event-based versus process-based informed consent to address scientific evidence and uncertainties in ionizing medical imaging” by Recchia et al