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MicroRNAs (miRNAs ) 是小 RNA 分子(约 22 核苷酸渴望) 参加基因表示的 post-transcriptional 规定(陈和 Rajewsky 2007 ) 。自从他们的发现千这些 RNA 被报导了。这些小分子被显示了在大量生物、病理学的过程起一个重要规章的作用(Brennecke 等 2003Cuellar 和 McManus 2005Lim 等 2005 ) 。最近 miRNAs 在浆液血浆尿和其它被发现了身体液体(陈等 2008威伯等 2010 ) 。有趣地这些细胞外的 miRNAs 的表示侧面与各种各样的疾病被相关他们可以在诊断并且监视人的疾病被用作 biomarkers (陆等 2005 ) 。

Small RNA existed in commercial reverse transcriptase: primary evidence of functional small RNAs