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The difference between arterial and end-tidal partial pressure of carbon dioxide (ΔCO 2 ) is a measure of alveolar dead space, commonly evaluated intraoperatively. Given its relationship to ventilation and perfusion, ΔCO 2 may provide prognostic information and guide clinical decisions. We hypothesized that higher ΔCO 2 values are associated with occurrence of a composite outcome of re-intubation, postoperative mechanical ventilation, or 30-day mortality in patients undergoing non-cardiac surgery.

Difference between arterial and end-tidal carbon dioxide and adverse events after non-cardiac surgery: a historical cohort study