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To determine whether ketamine added to morphine or hydromorphone patient-controlled analgesia (PCA) provides clinically relevant reductions in postoperative pain, opioid requirements, and adverse events when compared with morphine or hydromorphone PCA in adults undergoing surgery.

canadian journal of anaesthesia/canadian journal of anesthesia

Addition de kétamine à la morphine ou l’hydromorphone dans l’analgésie contrôlée par le patient pour les douleurs postopératoires aiguës chez l’adulte: revue systématique et méta-analyse des essais randomisés