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Résumé En MSOME (high-magnification motile sperm organelle morphology examination), certains spermatozoïdes jugés normaux au grossissement × 400 ou × 200 peuvent présenter des vacuoles céphaliques. Si la large vacuole est décrite comme une empreinte de pouce nucléaire, la nature des vacuoles pourrait dépendre de leur taille, du nombre, de leur localisation et de leur profondeur. Cette revue de la littérature débat de la nature des vacuoles, analyse les résultats obtenus en IMSI (intracytoplasmic morphologically selected sperm injection) et en liste les indications. Abstract MSOME (high-magnification motile sperm organelle morphology examination) has shown that some spermatozoa, which appear morphologically normal when viewed at × 400 or × 200, present defects such as cephalic vacuoles when viewed under high magnification. The large vacuole is described as a nuclear thumbprint, but the nature may depend on the size, number, position and depth of the vacuole. This review summarizes the data available on the nature of vacuoles, analyzes the results of IMSI (intracytoplasmic morphologically selected sperm injection) and lists its potential indications.

De la nature des vacuoles spermatiques aux résultats et indications de l’IMSI (intracytoplasmic morphologically selected sperm injection)