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Caffeine is a well-established performance enhancing nutritional supplement in a young healthy population, however far less is known about how its ergogenicity is affected by increasing age. A recent review has highlighted the value of studies examining the direct effect of caffeine on isolated skeletal muscle contractility, but the present work is the first to assess the direct effect of 70µM caffeine (physiological maximum) on the maximal power output of isolated mammalian muscle from an age range representing developmental to early ageing.

the journal of nutrition, health and aging/the journal of nutrition, health and aging

Is the ergogenicity of caffeine affected by increasing age? The direct effect of a physiological concentration of caffeine on the power output of maximally stimulated edl and diaphragm muscle isolated from the mouse