Open AccessA novel diagnostic method targeting genomic instability in intracystic tumors of the breast
Author(s) -
Masahiro Oikawa,
Hiroshi Yano,
Megumi Matsumoto,
Ryota Otsubo,
Kenichiro Shibata,
Tomayoshi Hayashi,
Kuniko Abe,
Naóe Kinoshita,
Koh-ichiro Yoshiura,
Takeshi Nagayasu
Publication year - 2014
Publication title -
breast cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.131
H-Index - 51
eISSN - 1880-4233
pISSN - 1340-6868
DOI - 10.1007/s12282-013-0516-9
Subject(s) - surgical oncology , medicine , genome instability , breast cancer , cancer research , oncology , bioinformatics , cancer , genetics , dna , biology , dna damage
Even after needle biopsy, the preoperative differential diagnoses of intracystic tumors of the breast are challenging because of their nonspecific radiological characteristics and subtle cytological and histological appearance. The aim of this study is to investigate a novel diagnostic method, targeting genomic instability (GIN) in intracystic tumors of the breast, using tumor DNA from samples obtained by fine-needle aspiration biopsy (FNAB).
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