Open AccessA FAILED CANCER PARADIGM: implications for cancer risk assessment and patients
Author(s) -
Calabrese Edward J.
Publication year - 2019
Publication title -
journal of cell communication and signaling
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.329
H-Index - 44
eISSN - 1873-961X
pISSN - 1873-9601
DOI - 10.1007/s12079-019-00526-6
Subject(s) - causation , cancer , cancer incidence , remedial education , medicine , risk analysis (engineering) , intensive care medicine , risk assessment , environmental health , psychology , computer science , political science , mathematics education , computer security , law
This commentary highlights the unique failures of environmental regulatory standards and related remedial actions to significantly reduce human cancer risks and the failure of cancer therapeutics to significantly impact cancer incidence and survival statistics despite vast resources allocated to both areas over the past half century. These dramatic institutional, scientific, medical, and regulatory failures suggest that current scientific understandings of cancer and its causation are seriously flawed and in need of a new objective re‐appraisal.