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The incidence of perioperative infection after segmental tumor endoprosthetic replacement in previous reports varies from a high of 7.4% to a low of 2.6%. Appropriate antibiotic use for this group is unknown and controversial, whereas the relationship of antibiotic use and perioperative infection is unclear.

Perioperative Infection Rate in Patients with Osteosarcomas Treated with Resection and Prosthetic Reconstruction