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Perioperative subcutaneous tissue oxygen tension (PsqO 2 ) is substantially reduced in obese surgical patients. Goal-directed fluid therapy optimizes cardiac performance and thus tissue perfusion and oxygen delivery. We therefore tested the hypothesis that intra- and postoperative PsqO 2 is significantly reduced in obese patients undergoing standard fluid management compared to goal-directed fluid administration.

Effect of Intraoperative Goal-Directed Fluid Management on Tissue Oxygen Tension in Obese Patients: a Randomized Controlled Trial