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Atrial Fibrillation (AF) is the most common sustained arrhythmia encountered in clinical practice, with increasing prevalence in the aging population. About 2.2 million patients in the United States and 4.5 million patients within the European Union have AF.1 The most feared and devastating complications of AF are thromboembolism and ischemic stroke. About 15–20 % of patients suffering from AF develop strokes.2 In view of an aging population, the higher physiological propensity for bleeding in the elderly and the overwhelming issues of polypharmacy, the decision for the use of anticoagulation is critical.

journal of general internal medicine

Capsule Commentary on Andrade et al., Clinical Benefit of American College of Chest Physicians versus European Society of Cardiology Guidelines for Stroke Prophylaxis in Atrial Fibrillation