English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Synaptic strength is modified by the temporal coincidence of synaptic inputs without back-propagating action potentials (BPAPs) in CA1 pyramidal neurons. In order to clarify the interactive mechanisms of associative long-term potentiation (LTP) without BPAPs, local paired stimuli were applied to the dendrites using high-speed laser uncaging stimulation equipment. When the spatial distance between the paired stimuli was &lt;10 micrometer, nonlinear amplification in excitatory postsynaptic potential summation was observed. In the time window from -20 to 20 ms, supralinear amplification was observed. Supralinear amplification was modulated by antagonist of voltage-gated Na(+)/Ca(2+) channels and NMDA-type glutamate receptors. These results are closely related to the spatiotemporal-characteristics of associative LTP without BPAPs. This study proposes an essential aspect of dendritic information processing.

cognitive neurodynamics

Spatiotemporal characteristics of synaptic EPSP summation on the dendritic trees of hippocampal CA1 pyramidal neurons as revealed by laser uncaging stimulation