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The aim of this study was to evaluate the fertility status, milk output, mortality, and body thermoregulation of rabbit does as affected by different levels of multi-enzyme extracts (EZ) in their diets. A total of 120 Hy-Plus rabbit does were divided into four comparable experimental groups (n = 30 does per group). Animals of each group were divided in six pens (five animals per pen), and each pen was used as an experimental unit. The first group was kept untreated and fed a commercial diet alone without enzyme extracts (EZ0), while the other groups were fed the same diet but supplemented with 1 (EZ1), 3 (EZ3), and 5 (EZ5) kg/ton of enzyme extracts, respectively. Feeding EZ additive increased (P &lt; 0.05) conception and kindling rates, litter size and weight at birth, and litter size and bunny weight at weaning, with decreasing (P &lt; 0.05) abortion rate. Moreover, total milk yield increased (P &lt; 0.05) with increasing level of enzyme supplementation. Pre-weaning mortality decreased (P &lt; 0.05) with EZ inclusion. Signs of vitality (rectal temperature, skin temperature, earlobe temperature, respiration rate, and pulse rate) were improved with EZ inclusion. For all results, 5 kg EZ/ton of feed was more effective than 1 and 3 kg EZ/ton feed. It can be concluded that supplementation of EZ in rabbit diet decreased mortality rate and enhanced fertility status and milk output.

Fertility, mortality, milk output, and body thermoregulation of growing Hy-Plus rabbits fed on diets supplemented with multi-enzymes preparation