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Modeling and control of diabetes mellitus (DM) are difficult due to the highly nonlinear attitude, time-delay effects, the impulse kind input signals and the lack of continuously available blood glucose (BG) level to be regulated. Regarding the mentioned problems, identification of DM model is crucial. Furthermore, due to the lack of information about the internal states (which cannot be measured in everyday life) and because the BG level is not available in every moment over time, adaptive robust control design method regardless exact model dependency would successfully handle these unfavorable effects without simplifications. The recently developed nonlinear robust fixed point transformation (RFPT)-based controller design method requires only a roughly approximate model in order to realize the controller structure. Moreover, parallel simulated approximate models-in order to provide additional internal information-can be used with the method. In this paper, the usability of the novel RFPT-based technique is demonstrated on the physiological problem of diabetes.

A robust fixed point transformation-based approach for type 1 diabetes control