Open AccessInflammation, T-Cell Phenotype, and Inflammatory Cytokines in Chronic Kidney Disease Patients Under Hemodialysis and its Relationship to Resistance to Recombinant Human Erythropoietin Therapy
Author(s) -
Elı́sio Costa,
Margarida Lima,
João Moura,
Susana Rocha,
Petronila RochaPereira,
Elisabeth Castro,
Vasco Miranda,
Maria Faria,
Alfredo Loureiro,
Alexandre Quintanilha,
Luı́s Belo,
Alice SantosSilva
Publication year - 2008
Publication title -
journal of clinical immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.739
H-Index - 96
eISSN - 1573-2592
pISSN - 0271-9142
DOI - 10.1007/s10875-007-9168-x
Subject(s) - medicine , erythropoietin , immunology , hemodialysis , cytokine , kidney disease , cd8 , inflammation , t cell , lymphocyte , endocrinology , immune system
Resistance to recombinant human erythropoietin (rhEPO) occurs in some chronic kidney disease (CKD) patients, which may be due to enhanced systemic inflammatory response and to the erythropoiesis-suppressing effect of pro-inflammatory cytokines, some of which are produced by T cells.
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