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The objective of this study was the elucidation of the possible role of the single-nucleotide polymorphisms (SNP) at position -29 and 2039 of the FSH receptor gene (FSHR) as independent predictive markers of ovarian response. Indeed, the tailoring of reproductive treatments is crucial for both maximizing the success of IVF patients and obtaining a reduction in hypo- or hyper-response rates.

journal of assisted reproduction and genetics

The carriers of the A/G-G/G allelic combination of the c.2039 A&gt;G and c.-29 G&gt;A FSH receptor polymorphisms retrieve the highest number of oocytes in IVF/ICSI cycles