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Isotope-labeled antiviral drug Triazavirin containing 2 H, 13 C, and 15 N atoms in its structure has been synthesized. 13 C 2 H 3 I and KS 13 CN served as donors of 13 C isotopes. The use of 13 С-MeI containing 2 H atoms made it possible to additionally incorporate deuterium labels into the structure of the compound. The 15 N atoms were incorporated using 15 N-enriched sodium nitrite, aminoguanidine carbonate, and ethyl nitroacetate. The resulting 2 H 3 , 13 C 2 , 15 N 3 -Triazavirin was characterized by NMR spectroscopy.

Antiviral drug Triazavirin, selectively labeled with 2H, 13C, and 15N stable isotopes. Synthesis and properties