English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Purpose We compared trajectories of vasomotor symptoms (VMS) and their risk factors in women with breast cancer (BrCa) to those of cancer-free controls. Methods Data were from 15 nearly annual follow-up visits (1996–2017) of the multi-racial/ethnic cohort of midlife women enrolled in the Study of Women’s Health Across the Nation (SWAN). We compared women with incident BrCa to controls for patterns of VMS, controlling for risk factors identified in bivariate analyses using multivariable longitudinal analyses. Results Characteristics at study entry largely did not differ between cases ( n  = 151) and controls ( n  = 2161). Adjusted  prevalence  of  any  VMS increased significantly among cases from diagnosis to 2.75 years post diagnosis [per-year adjusted odds ratio (aOR) = 1.76, 95% confidence interval (CI) 1.39–2.24], peaking at 2.75 years post diagnosis, whereas prevalence was stable among controls in this interval [aOR = 1.04, 95% CI 0.99–1.11]. Beyond 2.75 years post diagnosis,  prevalence  declined significantly in cases [aOR = 0.72, 95% CI 0.61–0.84] and less in controls [aOR = 0.96, 95% CI 0.92–1.00]. Patterns were similar for  frequent  VMS. Adjustment for tamoxifen use slightly reduced the per-year OR for  any prevalent  VMS post diagnosis, partially explaining excess VMS in cases. Other treatments were unassociated with VMS. Conclusions Patterns of prevalent VMS reporting differed significantly between cases and controls, particularly post diagnosis, the latter only partially explained by tamoxifen use among cases. Risk factors for VMS largely did not differ between cases and controls.

Vasomotor symptoms in midlife women with incident breast cancer: pink SWAN