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Cardiac dysfunction risk associated with intravenous trastuzumab (H IV) treatment may differ in real-world practice versus randomized trials. We investigated cardiac events in patients with HER2-positive early breast cancer (EBC) treated with H IV as adjuvant therapy in routine practice.

breast cancer research and treatment

A real-world study of cardiac events in &gt; 3700 patients with HER2-positive early breast cancer treated with trastuzumab: final analysis of the OHERA study