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In fully-developed pressure-driven flow, the spreading of a dissolved soluteis enhanced in the flow direction due to transverse velocity variations in aphenomenon now commonly referred to as Taylor-Aris dispersion. It is wellunderstood that the characteristics of the dispersion are sensitive to thechannel's cross-sectional geometry. Here we demonstrate a method formanipulation of dispersion in a single rectangular microchannel via controlleddeformation of its upper wall. Using a rapidly prototyped multi-layermicrochip, the channel wall is deformed by a controlled pressure sourceallowing us to characterize the dependence of the dispersion on the deflectionof the channel wall and overall channel aspect ratio. For a given channelaspect ratio, an optimal deformation to minimize dispersion is found,consistent with prior numerical and theoretical predictions. Our experimentalmeasurements are also compared directly to numerical predictions using anidealized geometry.

Dispersion control in pressure-driven flow through bowed rectangular microchannels