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In the spring of 2013, a newly pathogenic H7N9 influenza virus emerged in people in China, likely associated with wild and domestic birds (Kageyama et al. 2013). Marking the exact scenario that public health experts had feared—people were being infected, getting sick, and dying without the source of the virus being rapidly and definitively identified. In the absence of a clear understanding of the mode of transmission, early control of this epidemic proved difficult, especially since the most likely suspect reservoirs, animals being sold in markets, were not exhibiting the signs of illness that would help officials target mitigation measures and help citizens avoid exposure. Strict safety measures were enacted, including closures of markets that sell live birds and culling of animals in areas where patients have been diagnosed with confirmed cases. The associated costs of control and treatment of the sick, including secondary loss of poultry, were increased because interventions could not be efficiently targeted at the source of infection or the drivers of the virus’ emergence from that source.

Joint China-US Call for Employing a Transdisciplinary Approach to Emerging Infectious Diseases