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Lung cancer has become the most common cancer and the leading cause of cancer-related death in China [1]. Radiotherapy is commonly considered the main therapeutic modality for non-operative lung cancer. During the course of radiation treatment, tumor regression has been observed using electronic portal images, repetitive computed tomography (CT) scanning, and mega-voltage CT (MVCT) [2–5]. Adaptive radiotherapy for tumor volume changes, in which one adjusts a treatment plan to account for patient anatomical variations over a treatment course, has been proposed to improve tumor dose coverage or better spare normal structures [6]. However, adaptive planning is a very time-consuming process that may increase resource utilization and physician workDosimetric consequences of tumor volume changes after kilovoltage cone-beam computed tomography for non-operative lung cancer during adaptive intensity-modulated radiotherapy or fractionated stereotactic radiotherapy

oncology and translational medicine/oncology and translational medicine

Dosimetric consequences of tumor volume changes after kilovoltage cone-beam computed tomography for non-operative lung cancer during adaptive intensity-modulated radiotherapy or fractionated stereotactic radiotherapy