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DC MEG shifts, similarand complex in waveform, wereobserved in visually inducedmigraine with aura patients similarto spontaneous aura but not controls.Multiple cortical areas were activatedin visually induced and spontaneousaura patients. In normal subjectsactivation was only observed inthe primary visual cortex. Resultssupport a spreading depression–likeneuroelectric event as the basis ofmigraine aura that can arise spontaneouslyor be visually triggered inwidespread regions of hyperexcitableoccipital cortex.

Visual stress–induced migraine aura compared to spontaneous aura studied by magnetoencephalography