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Peritoneal lavage cytology is an excellent prognostic determinant but lacks sensitivity. Quantification of carcinoembryonic antigen (CEA) mRNA in peritoneal washes by real-time reverse-transcriptase polymerase chain reaction (RT-PCR) was found to be a more sensitive method to detect free cancer cells. It may be beneficial to explore, by the same method, a sample of the omentum, which is known to harbor cancer cells before the establishment of gross peritoneal metastasis.

gastric cancer

Quantitative detection of disseminated cancer cells in the greater omentum of gastric carcinoma patients with real-time RT-PCR: a comparison with peritoneal lavage cytology