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Phyllodulcin, a sweet-tasting compound extracted from Hydrangea macrophylla var. thunbergii , has recently received attention as a natural intense alternative sweetener with beneficial health effects. This study was conducted to determine the sweetness potency of phyllodulcin, relative to that of sucrose and to elucidate its sensory profile. Phyllodulcin solution was prepared by dissolving it in 1% ethanol (v/v) at 50°C. Relative sweetness to that of 3% sucrose in 1% ethanol solution was determined using the two-alternative forced-choice test. The sensory profile was obtained based on the descriptive analysis of 10 trained panelists. The relative sweetness of phyllodulcin was 434.8. Phyllodulcin was characterized by its bitterness, alcohol flavor, cooling sensation, and astringent aftertaste, but the persistence and onset of the sweetness of phyllodulcin were similar to those of sucrose. Further studies are required to improve the sweetness quality of phyllodulcin for facilitating its use in industrial applications by reducing its unfavorable flavor attributes.

Relative sweetness and sweetness quality of phyllodulcin [(3R)-8-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-3,4-dihydro-1H-isochromen-1-one]