English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Immunoglobulin A nephropathy (IgAN) is the most common form of glomerulonephritis characterized by predominant IgA deposits in glomerular mesangium. By means of a genome-wide case-control association study, we previously demonstrated that eight single-nucleotide polymorphisms (SNPs) within the selectin gene cluster are significantly associated with IgAN. Here we provide more detailed information of variations corresponding to selectin loci, consisting of 88 SNPs and two insertion-deletion polymorphisms in the Japanese population: 27 in 5' flanking regions, 1 in 5' untranslated regions, 6 within coding regions, 46 in introns, 4 within 3' untranslated regions, and 4 in 3' flanking regions. The SNP map presented here will be a useful resource not only for examining the relationships between selectin genotypes and susceptibility to the IgAN phenotype, but also for analyzing gene scans of complex diseases mapped to this local segment on chromosome 1.

High-resolution SNP map in the 55-kb region containing the selectin gene family on chromosome 1q24–q25