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Purpose To explore the long-term oncological results of self-expanding metal stents (SEMS) as a surgical transition compared with those of simple emergency surgery. Methods A systematic review of studies involving long-term tumour outcomes comparing SEMS with emergency surgery was conducted. All studies included information on 3-year and 5-year survival rates, 3-year and 5-year disease-free survival (DFS) rates, and local and overall recurrence rates; the results were expressed as odds ratios. Results Overall, 24 articles and 2508 patients were included, including 5 randomised controlled trials, 3 prospective studies, and 16 retrospective studies. The 3-year survival rate (odds ratio (OR) = 0.88, 95% confidence interval (CI) 0.69–1.12,  P  = 0.05), 5-year survival rate (OR = 0.91, 95% CI 0.70–1.17,  P  = 0.67), 3-year DFS rate (OR = 1.14, 95% CI 0.91–1.42,  P  = 0.65), 5-year DFS rate (OR = 1.35, 95% CI 0.91–2.02,  P  = 0.17), overall recurrence rate (OR 1.04, 95% CI 0.77–1.41,  P  = 0.14), and local recurrence rate (OR 1.37, 95% CI 0.84–2.23,  P  = 0.92) were determined. There was no significant difference between the randomised and observational studies in the subgroup analysis, and the 5-year survival rate was higher in studies with a stent placement success rate of ≥ 95%. Conclusion SEMS implantation was a viable alternative in malignant left colon obstruction as a transition to surgery; its long-term survival results, including 5-year DFS and overall survival, were equivalent to those of emergent surgery.

international journal of colorectal disease

Long-term tumour outcomes of self-expanding metal stents as ‘bridge to surgery’ for the treatment of colorectal cancer with malignant obstruction: a systematic review and meta-analysis