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Immune checkpoint blockade (ICB) and BRAF V600 -targeted therapy have demonstrated substantial clinical efficacy for patients with stage 4 melanoma in clinical trials; however, their impact on survival and barriers to treatment in the "real-life" setting remains unknown.

cancer immunology, immunotherapy/cancer immunology and immunotherapy

Management of metastatic melanoma: improved survival in a national cohort following the approvals of checkpoint blockade immunotherapies and targeted therapies