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The aims of this study were to calculate bone lesion absorbed doses resulting from a weight-based administration of 223 Ra-dichloride, to assess the relationship between those doses and corresponding 18 F-fluoride uptake and to assess the potential of quantitative 18 F-fluoride imaging to predict response to treatment.

european journal of nuclear medicine and molecular imaging

The potential of 223Ra and 18F-fluoride imaging to predict bone lesion response to treatment with 223Ra-dichloride in castration-resistant prostate cancer