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Amyloid-beta (Aβ) peptides are involved in the inflammatory pathology of atherosclerosis. 18 F-Florbetaben is a PET tracer for clinical imaging of cerebral Aβ plaques in Alzheimer's disease (AD). We sought to determine whether specific uptake of 18 F-florbetaben in the carotid arteries can be identified using a fully integrated hybrid PET/MRI system and whether this uptake is associated with clinical cardiovascular disease (CVD) risk factors.

Feasibility of in vivo 18F-florbetaben PET/MR imaging of human carotid amyloid-β