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Colorectal cancer is the second leading cause of death and the fourth most commonly diagnosed cancer in the USA [1]. One form, rectal cancer, defined as cancer growing within 12 cm of the anal verge [2], is challenging because of its unique anatomical characteristics, critical position and therapeutic options (aimed at preserving pelvic floor integrity, sphincter continence and genitourinary functions).

The emerging role of FDG PET/CT in rectal cancer management: is it time to use the technique for early prognostication?