Open AccessHTR1B as a risk profile maker in psychiatric disorders: a review through motivation and memory
Author(s) -
Antonio Drago,
Silvia Alboni,
N. Brunello,
Diana De Ronchi,
Alessandro Serretti
Publication year - 2009
Publication title -
european journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.845
H-Index - 108
eISSN - 1432-1041
pISSN - 0031-6970
DOI - 10.1007/s00228-009-0724-6
Subject(s) - mnemonic , psychology , recall , psychiatry , association (psychology) , vortioxetine , cognitive psychology , clinical psychology , psychotherapist , anxiety , antidepressant
Serotonin receptor 1B (HTR1B) is involved in the regulation of the serotonin system, playing different roles in specific areas of the brain. We review the characteristics of the gene coding for HTR1B, its product and the functional role of HTR1B in the neural networks involved in motivation and memory; the central role played by HTR1B in these functions is thoroughly depicted and show HTR1B to be a candidate modulator of the mnemonic and motivationally related symptoms in psychiatric illnesses.
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