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Individuals vary in the extent to which they attribute incentive salience to reward cues. Discrete food and drug (cocaine and opioid) cues become more attractive, eliciting approach toward them, and more "wanted," in that they serve as more effective conditioned reinforcers, in some rats (sign-trackers, STs), than in others (goal-trackers, GTs).

Individual variation in the motivational properties of a nicotine cue: sign-trackers vs. goal-trackers