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Syntaxin 1A is a candidate gene for Type II (non-insulin-dependent) diabetes mellitus, because it plays an important role in insulin secretion from the islet beta cells. We aimed to scan this gene for mutations or genetic markers that correlate with Type II diabetes.

diabetologia

Single nucleotide polymorphism ( D68D , T to C ) in the syntaxin 1A gene correlates to age at onset and insulin requirement in Type II diabetic patients