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We study holographic renormalization group flows from four-dimensional$\mathcal{N}=2$ SCFTs to either $\mathcal{N}=2$ or $\mathcal{N}=1$ SCFTs. Ourapproach is based on the framework of five-dimensional half-maximalsupergravity with general gauging, which we use to study domain wall solutionsinterpolating between different supersymmetric AdS$_5$ vacua. We show that aholographic RG flow connecting two $\mathcal{N}=2$ SCFTs is only possible ifthe flavor symmetry of the UV theory admits an ${\rm SO}(3)$ subgroup. In thiscase the ratio of the IR and UV central charges satisfies a universal relationwhich we also establish in field theory. In addition we provide several generalexamples of holographic flows from $\mathcal{N}=2$ to $\mathcal{N}=1$ SCFTs andrelate the ratio of the UV and IR central charges to the conformal dimension ofthe operator triggering the flow. Instrumental to our analysis is a derivationof the general conditions for AdS vacua preserving eight supercharges as wellas for domain wall solutions preserving eight Poincare supercharges inhalf-maximal supergravity.

Holographic RG Flows for Four-dimensional $\mathcal{N}=2$ SCFTs