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Quantum chromodynamics (QCD) rigorously predicts the existence of bothnonperturbative intrinsic and perturbative extrinsic heavy quark contents ofnucleons. In this article we discuss the heavy quark electroproduction onprotons induced by the Fock states $|uud+g\rangle$ of three valence quarks inthe proton and a nonperturbative gluon, and the $|uud+Q\bar Q\rangle$non-perturbative state of three valence quarks and a heavy quark-antiquarkpair. The first one gives the perturbative contribution when the gluon producesa heavy quark pair, while the second is the intrinsic part, and they produceamplitude interference. We use nonperturbative light-front wavefunctions forthese Fock states, which are computed using the color-confining light-frontholographic QCD theory. Due to interference of the amplitudes corresponding tothe intrinsic and extrinsic heavy quark contribution to the proton a novel $Q$vs. $\bar Q$ asymmetry emerges in the differential cross section of theelectroproduction off a proton $d^2\sigma_{e^-p}/(dx dQ^2)$. Our analysisproposed a novel asymmetry in QCD between intrinsic and extrinsic heavy quarkcontent in nucleon and provides new insights into the physics of heavy quarkphenomena in QCD at the amplitude level. This asymmetry is similar to theBrodsky-Gillespie asymmetry discovered before in QED case and confirmed atDESY.

QCD at the amplitude level: Fock state interference in heavy quark electroproduction