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We study the $\mathcal N=2$ field theory realized by D3-branes on the${\mathbb C}^2/{\mathbb Z}_2$ orbifold. The dual supergravity solution exhibitsa repulson singularity cured by the enhancon mechanism. By comparing the openand closed string descriptions of a probe D-instanton, we can compute the exactnon-perturbative profile of the supergravity twisted field, which determinesthe supergravity background. We then show how the non-trivial IR physics of thefield theory translates into the stringy effects that give rise to the enhanconmechanism and the associated excision procedure.

D-instanton probe and the enhan\c{c}on mechanism from a quiver gauge theory