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We analyze the constraints imposed by Higgs vacuum stability on models with new fermions beyond the Standard Model. We focus on the phenomenology of Higgs couplings accessible at the Large Hadron Collider. New fermions that affect Higgs couplings lead to vacuum instability of the Higgs potential. Above the scale of vacuum instability, bosonic states must stabilize the potential, implying a cut-off to the pure fermion model. Conservatively tuning the models to produce the maximal cut-off for a given Higgs coupling effect, we show that observing a deviation in the Htt , H -diphoton, or H -digluon coupling, larger than 20%, would require that new bosons exist in order to stabilize the Higgs potential below about 100 TeV. For generic parameter configurations, and unless the new fermions are made as light as they can possibly be given current experimental constraints, observing a 10% deviation in any of these couplings would suggest an instability cut-off below 10-100 TeV. Similarly, if new bosons are absent up to a high scale, then a deviation in the Hbb or Hττ coupling, larger than about 20%, should be accompanied by a sizable deviation in the Zbb or Zττ couplings that can be conclusively tested with electroweak precision measurements at planned lepton colliders

Vacuum stability bounds on Higgs coupling deviations in the absence of new bosons