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Background: Both intrinsic and acquired multidrug resis- tance play an important role in the insurgence of tubercu- losis. Detailed knowledge of the molecular basis of drug recognition and transport by multidrug transport systems is required for the development of new antibiotics that are not extruded or of inhibitors that block the multidrug transporter and allow traditional antibiotics to be effective. Materials and Methods: We have undertaken the inven- tory of the drug transporters subfamily, included in the major facilitator superfamily (MFS), encoded by the com-

The Multidrug Transporters Belonging to Major Facilitator Superfamily (MFS) in Mycobacterium tuberculosis