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N-acetylcysteine may prevent acute kidney injury after cardiac surgery. To determine if N-acetylcysteine warrants definitive evaluation in a large multicentre trial, we evaluated its effects on a surrogate outcome, estimated glomerular filtration rate (eGFR), in a randomized trial.

canadian journal of anaesthesia/canadian journal of anesthesia

Recours à la N-acétylcystéine pour prévenir une atteinte rénale aiguë chez les patients de chirurgie cardiaque souffrant d’une insuffisance rénale modérée préexistante