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METHODS: Forty-two non-diabetic patients undergoing OPCAB were enrolled in this study. TEA was installed more than 1 h before application of heparine at levels of T2 to T4; analgesia was provided by 8 ml of bupivacaine 0.25% 15 min prior to surgery and extubation, and 10 ml/h during and up to 72 h after surgery of one of the following regimens: bupivacaine 0.125% solely, bupivacaine 0.125% with fentanyl 3 μg/ml or bupivacaine 0.125% with clonidine 0.6 μg/ml. Patients were block-randomized for one of the three treatments. Patient data, cortisol and glucose levels were compared. Multi-comparison ANOVA was used to compare the data, P < 0.05.

Stress protection of different solutions of thoracic epidural anesthesia for immediate extubation after off-pump cardiac surgery (OPCAB)