English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The haemodynamic effects of equi-anaesthetic doses of alphaprodine and sulfentanil were evaluated in mongrel dogs ventilated mechanically. The effects of the addition of atropine were assessed for each drug, as were the effects of breathing nitrous oxide 60 per cent with oxygen and nitrogen 60 per cent with oxygen and the administration of naloxone. The results of this study demonstrate that anaesthetic doses of sulfentanil produce little change in cardiovascular dynamics in atropinized dogs and only small changes in dogs without atropine premedication, irrespective of the infusion rate. In contrast alphaprodine causes a significant cardiovascular depression irrespective of the presence or absence of atropine premedication. Naloxone reversed the anaesthetic effects in all dogs anaesthetized with alphaprodine but did not reverse the anaesthetic state in any dog given sulfentanil. Our data suggest that sulfentanil deserves evaluation as a narcotic anaesthetic in man.

Comparison of haemodynamic effects of anaesthetic doses of alphaprodine and sulfentanil in the dog